July 6th, 2007 by Paul Johnson

11-OXO is a new supplement for 07, that has come out from the innovative company called Ergopharm. This supplement has revolutionized OTC supplement industry once again, like many of Patrick Arnold’s previous supplements. Arnold first revolutionized the supplement industry, when he came out with the potent hormonal products, 1-AD and 6-OXO.

What is 11-OXO?

11-OXO (chemical name Adrenosterone) main action is it lowers cortisol levels in the body. Cortisol is the main catabolic (muscle-eating) hormone in the body and it also promotes fat gain. Cortisol and testosterone also work in an inverse relationship, so high cortisol levels lowers your testosterone levels. 11-OXO (Adrenosterone) is called a first selective inhibitor of 11b-hydroxysteroid dehydrogenase type I reductase. What this means is 11-OXO acts as a competitive inhibitor, preventing cortisone from attaching to the 11b-hydroxysteroid dehydrogenase type I reductase. 11-OXO competes at the receptor and therby keeps cortisone from attaching and converting to cortisol through the enzyme. 11-OXO is actually found naturally in the body and is released by the adrenal glands. The body uses it as a way to help regulate cortisol levels from getting too high.

Does it work?

Patrick Arnold is the leading steroid chemical expert in the bodybuilding industry. You can be sure that any innovative supplement he comes out with, will be backed with real sciencetific knowledge. A search on pubmed shows dozens of studies, where Adrenosterone plays a integral part in cortisol and steroid metabolism. Ancedotally, it has been show to work from thousands of bodybuilders who have tried 11-oxo.

11-oxo effects on the body:
Reducing cortisol should help give you significant gains in muscle and fat loss simultaneously. You should also have increased muscle hardness and strength. 11-oxo is good for gaining more lean gains while bulking, and maintaining muscle and losing more fat while cutting.

11-OXO also has a slight pro-hormone nature as it converts to an active weak steroid, according to Patrick Arnold. This will create an even more powerful anabolic effect due to the duel nature of this compound.

11-OXO side effects:

Unfortunately, 11-OXO is not side effect free due to the secondary prohormone nature of the compound. It is recommended for people over 21 and those comfortable using hormone products. It should also be cycled to allow time for natural test production to go to normal afterwards.

  1. Jakob on July 30th, 2007

    This is exactly what I expected to find out after reading the title O. Thanks for informative article

  2. Brian snow on April 28th, 2009

    11-oxo definitely works. When I hit a plateau I get on 11-oxo for a few weeks and break through my plateau easily in strength and size.

  3. […] is a relatively new supplement out by Ergopharms. You will want to read my previous article on 11-OXO to find out more about […]

  4. kevin on February 7th, 2011

    What does 11-oxo do to your libido or erectile performance during and after? Anyone tried it and what happened after? Also what was your age? Thanks!