Appetite Suppressant Supplements Really Work?

August 30th, 2007 by Paul Johnson

Many appetite suppressant supplements are touted for curbing your appetite. But is it really possible to do that? Researchers at Columbia University did a study on the nucleus incumbens and it's role in binge eating. The Nucleus incumbens is in the limbic system and it controls mood and feelings of satiation, including feeling "full". In the research they injected opioids into rats. The ones who had opioids injected ate 3 times as much fatty foods.

The result of the study showed that nucleus incumbens only controlled appetite AFTER they were full. This means that appetite suppressing supplements, should only work for preventing overeating, only after you first have become full. But is this really true? Everyone who has tried stimulants such as ephedrine have noticed a appetite suppressing effect. Some possible theories of mine on why this may be the case is that perhaps this study is faulty, or it only works in rats, or Ephedrine works in some other part of the brain or body to suppress appetite.

  1. Josh on February 1st, 2008

    I have to disagree with you here. Combine ephedrine HCL (24-50mg) and caffeine (200-400mg) and you have an effective appetite supressant. Increasing the ephedrine dosage to above what I have suggested here can kill my appetite alltogether, and at 250lbs 14% bodyfat I can put away 6000 calories per day with ease while bulking. Needless to say, combining caffeine and ephedrine should be done with EXTREME care and NEVER long term.

  2. admin on February 2nd, 2008

    Thanks for your input Josh. You have a good point, stimulants such as Ephedrine seem to have this effect. I was considering mentioning this when I originally wrote the article, but I didn’t have any studies supporting appetite suppression with stimulants other than ancedotal experience. I’ll update the article to reflect these questions.

  3. Bryan on July 14th, 2008

    Iam looking for a appitite supprescent that curves my cravings when iam at the office. My weakness is working on my computer and not having somthing to eat. If iam totally busy its not a big deal, but when it gets slow i find myself lookin for somthing to much on. Is ephedrine available- can a person take it and not interupt thier sleep habits???

  4. admin on July 19th, 2008

    Ephedrine will most certainly interrupt your sleeping habits if you take it in the late afternoon or later. Ephedrine can last sometimes well over 12 to 20 hours depending on the dose, so the later in the day you take it the more likely it will cause insomnia.